Radboud Research Round PLUS: Filip Swirski

Theme: Vascular damage & Infectious diseases and global health

22 October 2015 16:00 hrs. - 17:30 hrs.
Tuinzaal, route 706
Growth factors, inflammation and cardiovascular disease

Prof. Filip Swirski, MGH, Center for Systems Biology, Boston, USA


Gerard Rongen, Dept. of Internal Medicine, theme Vascular damage, Radboudumc

22-10-2015 16:00:0022-10-2015 17:30:00Europe/AmsterdamGrowth factors, inflammation and cardiovascular disease Tuinzaal, route 706Rimlsrimls@radboudumc.nl

Remarks / more information:



Theme: Vascular damage & Infectious diseases and global healthRRR Nieuw 2015

Cardiovascular disease claims more lives than any other worldwide. Atherosclerosis, a lipid-driven inflammatory process characterized by progressive leukocyte accumulation in the vessel wall, is frequently the underlying cause of myocardial infarction and stroke. In this talk I will discuss how hematopoietic cells participate in the cardiovascular system. I will elaborate how a family of growth factors influences leukocyte production and function in the blood, vessel wall, and heart. I will draw from our studies utilizing models of sepsis (systemic inflammation), atherosclerosis (vessel wall inflammation), and myocardial infarction (cardiac inflammation). I will provide a general synthesis of the various processes that occur during these seemingly different pathologies and outline the major questions that need to be answered in the future.




With reference to the following literature:

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