Seminar

Seminar

Date:
30 May 2011 00:00 hrs.
Location:
Title:
The micro-epidemiology of malaria transmission: options for targeted malaria control and challenges for the field evaluation of a malaria transmission blocking vaccine.
Speaker(s):

Dr. J.T. Bousema London School of Hygiene & Tropical Medicine, Department of Immunology & Infection, London, UK

Host(s):

Prof. Bart Kiemeney, Department of Epidemiology, Biostatistics and HTA, UMC Nijmegen.

30-05-2011 00:00:00Europe/AmsterdamThe micro-epidemiology of malaria transmission: options for targeted malaria control and challenges for the field evaluation of a malaria transmission blocking vaccine. Rimlsrimls@radboudumc.nl

Remarks / more information:

Teun-BousemaMalaria transmission is highly heterogeneous. Within a single village, some households may be exposed to malaria-infected mosquitoes at a rate that is tenfold higher than the village average. Understanding this heterogeneity in malaria transmission is pivotal for interpreting epidemiological findings and the planning of malaria control and elimination efforts. In this seminar, the consequences of heterogeneity in malaria transmission for the interpretation of longitudinal studies will be illustrated using examples from the field. Recent advances in detecting hotspots of malaria transmission by entomological, molecular, serological and remote sensing tools will be discussed. These tools have the potential to guide targeted malaria control efforts and will become increasingly important in areas that have adopted malaria elimination strategies. The characterization of micro-epidemiological patterns of malaria transmission can also form a cornerstone in the field evaluation of a malaria transmission blocking vaccine. For this, the challenges posed by sub-microscopic parasite carriage and multi-clone infections have to be overcome.



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