Seminar

Seminar

Date:
19 January 2011 00:00 hrs.
Location:
Title:
Genome-wide functional differences between HAT coactivator complexes.
Speaker(s):

Dr. Laszlo Tora, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Strasbourg, France

Host(s):

Dr. Gert Jan Veenstra

19-01-2011 00:00:00Europe/AmsterdamGenome-wide functional differences between HAT coactivator complexes. Rimlsrimls@radboudumc.nl

Remarks / more information:

Tora-LaszioOur main research interest is to study how specific protein coding genes are turned on and off in the nucleus of a given cell, during growth, differentiation and development. We use biochemical, genetic, cell biology, imaging and structural approaches to study the problem of control of gene expression in different metazoan organisms. The lab's research is broadly centred on three different axes, which all aim to better understand RNA polymerase II transcription: (i) the role of different proteins belonging in the TATA box binding protein (TBPs) protein family, (ii) the role of TBP-associated factor (TAF)-containing complexes (i.e. TFIID and SAGA); and (iii) the role of histone acetyl transferase (HAT)-containing chromatin remodelling coactivator complexes (i.e. SAGA and ATAC) in gene regulation.



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