Seminar: Chris Bakal, theme Cancer development and immune defence

Using statistical cell biology to understand the emergence of phenotypic heterogeneity in cancer cell populations

Date:
6 October 2015 14:00 hrs. - 15:00 hrs.
Location:
Figdor Lecture Theatre, 8th floor RIMLS Building, Geert Grooteplein 26-28, route 289
Title:
Using statistical cell biology to understand the emergence of phenotypic heterogeneity in cancer cell populations
Speaker(s):

Chris Bakal, Institute of Cancer Research, London, UK

Host(s):

Klaas Mulder, Dept. of Developmental Biology, RIMLS

06-10-2015 14:00:0006-10-2015 15:00:00Europe/AmsterdamUsing statistical cell biology to understand the emergence of phenotypic heterogeneity in cancer cell populations Figdor Lecture Theatre, 8th floor RIMLS Building, Geert Grooteplein 26-28, route 289Rimlsrimls@radboudumc.nl

Remarks / more information:

undefinedundefinedDr. Chris Bakal’s Dynamical Cell Systems Team uses genomic approaches and computational modelling to understand how complex biochemical signalling networks are ‘rewired’ during the development of cancer.

 

 

 

 

 

Key publications

  • A screen for morphological complexity identifies regulators of switch-like transitions between discrete cell shapes. Nat Cell Biol. 2013.
  • Visualizing cellular imaging data using PhenoPlot. Nat Commun. 2015.
  • Cell shape and the microenvironment regulate nuclear translocation of NF-κB in breast epithelial and tumor cells.  Mol Syst Biol. 2015.


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