Seminar: Dr. Christoph Dietrich

Computational Biology of RNA editing and circular RNAs

Date:
25 February 2015 11:45 hrs. - 13:00 hrs.
Location:
Figdor Lecture Theatre, 8th floor RIMLS Building, Geert Grooteplein 26-28, route 289
Title:
Computational Biology of RNA editing and circular RNAs
Speaker(s):

Dr. Christoph Dietrich, Max-Planck Institute for Biology of Ageing, Cologne, Germany

Host(s):

Dr. Armaz Aschrafi, Donders Institute for Brain, Cognition and Behavior Radboudumc

25-02-2015 11:45:0025-02-2015 13:00:00Europe/AmsterdamComputational Biology of RNA editing and circular RNAs  Figdor Lecture Theatre, 8th floor RIMLS Building, Geert Grooteplein 26-28, route 289Rimlsrimls@radboudumc.nl

Remarks / more information:

Dietrich _Christoph _cv [1]The flow of genetic information from DNA to proteins has been traditionally seen as a linear pathway with an RNA intermediate. Instead of just being an inert carrier of information, RNA editing modifies the primary sequence and changes in RNA localization influence the availability of RNA molecules. These emerging processes and interaction networks are subsumed under the term "post-transcriptional gene regulation" and have an impact on numerous cellular processes. 

 

 

Key Publications
•Differential protein occupancy profiling of the mRNA transcriptome. Genome Biol. ; 15:R15, 2014
•MOV10 Is a 5' to 3' RNA helicase contributing to UPF1 mRNA target degradation by translocation along 3' UTRs. Mol Cell.; 54:573-85, 2014
•The Pristionchus pacificus genome provides a unique perspective on nematode lifestyle and parasitism. Nat Genet.; 40:1193-8, 2008



<< back to all events