Seminar: Dr. Joost Gribnau

X chromosome inactivation, revisited

Date:
28 August 2013 00:00 hrs.
Location:
Figdor Lecture Theatre, 8th floor RIMLS Building, Geert Grooteplein 26-28, route 289
Title:
X chromosome inactivation, revisited
Speaker(s):

Dr. Joost Gribnau, Dept. of Reproduction and Development, Erasmus Medical Center, Rotterdam.

Host(s):

Prof. Henk Stunnenberg, Dept. of Mol. Biology, NCMLS, Nijmegen.

28-08-2013 00:00:00Europe/AmsterdamX chromosome inactivation, revisited Figdor Lecture Theatre, 8th floor RIMLS Building, Geert Grooteplein 26-28, route 289Rimlsrimls@radboudumc.nl

Remarks / more information:

Gribnau, JoostResearch in the Gribnau lab in the Erasmas Medical Center (Rotterdam) is mainly focused on genomic imprinting and X chromosome inactivation. His research group discovered that X chromosome inactivation is a stochastic process, and has recently identified the first X-encoded trans-acting factor involved in activation of the X chromosome inactivation process. Together, this work has led to a ground-breaking model with RNF12 as the key, dose-dependent activator of X-inactivation, which will be discussed in this seminar.



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