Seminar: Dr. Roman-Ulrich Müller

C. elegans as a model for longevity and tissue-protection

Date:
6 January 2014 00:00 hrs.
Location:
Figdor Lecture Theatre, 8th floor RIMLS Building, Geert Grooteplein 26-28, route 289
Title:
C. elegans as a model for longevity and tissue-protection
Speaker(s):

Dr. Roman-Ulrich Müller, department of Internal Medicine, University of Cologne, Germany

Host(s):

Prof. Peter Deen, department of Physiology, Radboudumc

06-01-2014 00:00:00Europe/AmsterdamC. elegans as a model for longevity and tissue-protection Figdor Lecture Theatre, 8th floor RIMLS Building, Geert Grooteplein 26-28, route 289Rimlsrimls@radboudumc.nl

Remarks / more information:

 

MMD Course: Oxygen in health and disease

Mueller _roman -ulrichThe nematode C. elegans is one of the most versatile and best established models for studying pathways mediating lifespan extension and cellular stress resistance. Interestingly, the pathways involved are highly conserved up to mammals and could be shown to increase stress resistance of human organs. Recently, we identified hypoxia inducible factor signaling to be one of the key mechanisms linking stress resistance and longevity. Understanding the molecular mechanisms underlying these phenomena is crucial for achieving organo-protection in the clinical setting characterized by an increasing number of age-related diseases.



<< back to all events