Seminar: Jan Huisken, theme Cancer development and immune defence

Reconstructing zebrafish development with smart light sheet microscopy

Date:
12 January 2016 13:00 hrs. - 14:00 hrs.
Location:
Figdor Lecture Theatre, 8th floor RIMLS Building, Geert Grooteplein 26-28, route 289
Title:
Reconstructing zebrafish development with smart light sheet microscopy
Speaker(s):

Jan Huisken, MPI-CBG Dresden, Germany

Host(s):

Leonie Kamminga, Dept. of Molecular Biology, RIMLS

12-01-2016 13:00:0012-01-2016 14:00:00Europe/AmsterdamReconstructing zebrafish development with smart light sheet microscopy Figdor Lecture Theatre, 8th floor RIMLS Building, Geert Grooteplein 26-28, route 289Rimlsrimls@radboudumc.nl

Remarks / more information:

undefinedThe overall goal in the Huisken lab is the systematic study of developmental processes in living organisms by noninvasive biomedical imaging techniques such as optical microscopy. Of primary interest is the investigation of organogenesis in zebrafish with special emphasis on the function and morphogenesis of the cardiovascular system and the endoderm. We develop novel quantitative microscopy tools and experimental strategies to understand and describe tissue dynamics on a cellular level. High-speed fluorescence microscopy is the primary tool to capture the dynamics of a heartbeat and the fate of single cells during organogenesis.  

 

 

Key Publications

  • Hyperspectral light sheet microscopy. Nat Commun;6:7990, 2015
  • The smart and gentle microscope. Nat Biotechnol; 33(8):815-8, 2015
  • Real-time multi-view deconvolution. Bioinformatics; 31:3398-400, 2015
  • Optical tomography complements light sheet microscopy for in toto imaging of zebrafish development. Development; 142:1016-20, 2015

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