Seminar: Prof. Chris Dobson

The Amyloid Phenomenon and Its Biological Significance

3 October 2014 14:00 hrs. - 15:00 hrs.
Location see remarks
The Amyloid Phenomenon and Its Biological Significance

Professor Chris Dobson, Master of St John's College (University of Cambridge) and awarded the Heineken Prize 2014 for Biochemistry and Biophysics


Prof. W. Huck, Radboud University

03-10-2014 14:00:0003-10-2014 15:00:00Europe/AmsterdamThe Amyloid Phenomenon and Its Biological Significance Location see

Remarks / more information:


DobsonThe Heineken Prize is among the most prestigious in the scientific community, and a recognition of lifetime achievement which is widely regarded as second only to a Nobel Prize. The award recognises Professor Dobson's achievements in helping to identify the root causes of so-called "modern" disorders, such as Alzheimer's and Parkinson's diseases.

Location: Lecture hall: HG00.303, Radboud University




Research Interests of prof. Dobson:

Our research interests are focused on protein molecules, and particularly on defining the fundamental principles by which they fold to generate function and biological activity, and yet can misfold to generate toxicity and disease. Our studies are highly interdisciplinary and collaborative, and make use of a very wide range of techniques, encompassing theory as well experiment (our primary activity). We are particularly interested in the discovery of the nature, properties, mechanism of formation and biological significance of the 'misfolded' amyloid state of proteins. Amyloid-related diseases include whole-body disorders such as the systemic amyloidoses, neuronal disorders such as Alzheimer's and Parkinson's diseases, and other organspecific disorders such as type II diabetes. Our major goals are the elucidation of the general molecular principles that underlie this whole family of medical conditions, which are now becoming a major threat to human health and social harmony across the modern world, and the generation of a firm foundation for the rational and effective prevention and treatment of these debilitating and usually fatal conditions.

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