Seminar: Prof. René Medema

Determinants of cell fate after DNA damage

Date:
13 April 2015 14:00 hrs. - 15:00 hrs.
Location:
Figdor Lecture Theatre, 8th floor RIMLS Building, Geert Grooteplein 26-28, route 289
Title:
Determinants of cell fate after DNA damage
Speaker(s):

Prof. René Medema, Director of Research, Netherlands Cancer Institute, Amsterdam

Host(s):

Dr. Klaas Mulder, Dept. of Molecular Developmental Biology, Radboudumc

13-04-2015 14:00:0013-04-2015 15:00:00Europe/AmsterdamDeterminants of cell fate after DNA damage Figdor Lecture Theatre, 8th floor RIMLS Building, Geert Grooteplein 26-28, route 289Rimlsrimls@radboudumc.nl

Remarks / more information:

undefinedundefinedAbstract 

Our group is interested in the molecular mechanisms of cell division. One major focus is to understand how cells recover from a DNA damaging insult, such as those caused by some anti-cancer drugs, which activates a checkpoint and triggers cell cycle arrest.

 

 

 

 

 

Key publications

  • Comparative phosphoproteomic analysis of checkpoint recovery identifies new regulators of the DNA damage response. Sci Signal, 6:rs9, 2013
  • Chromosome segregation errors as a cause of DNA damage and structural chromosome aberrations. Science, 333:1895-8, 2011


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