Seminar: Roel Verhaak, theme Rare cancers

Genomic analysis and tumor evolution of gliomas

Date:
22 March 2016 12:00 hrs. - 13:00 hrs.
Location:
Figdor Lecture Theatre, 8th floor RIMLS Building, Geert Grooteplein 26-28, route 289
Title:
Genomic analysis and tumor evolution of gliomas
Speaker(s):

Roel Verhaak, Dept. of Bioinformatics and Computational Biology & Dept. of Genomic Medicine, UT MD Anderson Cancer Center, Houston, USA

Host(s):

Pieter Wesseling, Dept. of Pathology, Radboudumc

22-03-2016 12:00:0022-03-2016 13:00:00Europe/AmsterdamGenomic analysis and tumor evolution of gliomas Figdor Lecture Theatre, 8th floor RIMLS Building, Geert Grooteplein 26-28, route 289Rimlsrimls@radboudumc.nl

Remarks / more information:

undefinedAfter being trained in the Netherlands (Radboudumc/Erasmus), Dr. Roel Verhaak moved to the USA. Based on the work he performed during a research fellowship in the Broad Institute of Massachusetts Institute of Technology and Harvard University, he published the well-known ‘Verhaak classifier’ which distinguishes clinically relevant subgroup of glioblastomas based on gene expression profiles. Since 2010 he is affiliated with the Department of Bioinformatics and Computational Biology and the Department of Genomic Medicine of the MD Anderson Cancer Center in Houston where currently he holds the position of Associate Professor. His contributions to the field of Molecular Neuro-Oncology are enormous. He has a leading role in The Cancer Genome Atlas Network that in the last five years published several landmark papers on the molecular landscape of diffuse gliomas using state of the art bio-informatics tools. 

Key Publications

  • Molecular profiling reveals biologically discrete subsets and pathways of progression in diffuse glioma. Cell; 2016 (in press).
  • Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas. N Engl J Med.;372:2481-98, 2015
  • The somatic genomic landscape of glioblastoma. Cell; 155:462-77, 2013.


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