A Personal Touch of Jessie van Buggenum

Jessie Van Buggenum

Please learn more about colleagues in our "Personal Touch" series setting employees in the spotlight. A light-hearted manner to learn about the colleagues you know and those you don't!.

This week: Jessie van Buggenum

 

 

 

 

 

1. Name & Nationality
Jessie van Buggenum, Dutch

2. When you were a kid what did you want to be when you grew up?
(Mathematics) teacher or opera singer

3. What was your previous academic training, where did you study?
BSc Biology and MSc Molecular Mechanisms of Disease in Nijmegen

4. What is your current function and what would you like to achieve?
I am a PhD student in de department of Molecular Developmental Biology in the group of Klaas Mulder.

Epidermal stem cells are able to self-renew and differentiate to maintain the upper layer of the skin. EGF Receptor activity is essential for epidermal stem cells, and inhibition EGFR leads to their differentiation. Cancer drugs that inhibit EGFR often cause skin toxicities in patients .The molecular mechanisms behind these processes are still not clear. We aim to elucidate the molecular mechanisms behind EGFR inhibitor induced differentiation of primary human keratinocytes.

Moreover, during my PhD I aim to develop a protein detection method that is able to detect 50-100 proteins in 1000s of populations in different conditions in one single experiment.

5. The RIMLS motto is 'to understand molecular mechanisms of disease'. What does this mean for you?
During high school I was intrigued by "DNA and RNA". I wanted to understand how cells regulate transcription and translation. For this reason I started my study biology. As I have learned over the years, cells are very complex and regulation takes place at many different levels. Small mistakes in these regulatory processes can have large effects and cause disease. Therefore, it is essential to understand the molecular mechanisms of healthy and diseased cells.

6. What is the biggest motivation in your work?
To feel excited about new projects and ideas.

7. What is your dream for the future?
As an enthusiastic scientist I strive to develop innovative projects by observing, learning and creating.

8. Fun-facts. State an interesting/obscure fact about yourself together with two that are false? Correct answer will be revealed to readers in the subsequent edition.
A: I meditate 5 times per week
B: I create my own words randomly
C: I love to eat Brussels sprouts

Correct answer will be revealed to readers in the subsequent edition.

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Correct answer of Jurjen Tel : B

State an interesting/obscure fact about yourself together with two that are false?

A: As a born Frisian I have skated the "Elfstedentocht" twice...
B: During vacations I become a passionate wildlife and bird photographer...
C: After work I turn into a semi-professional lean mean knitting machine...


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