A Personal Touch of Marije Behet

Behet, Marije 2017.jpg

Please learn more about colleagues in our "Personal Touch" series setting employees in the spotlight. A light-hearted manner to learn about the colleagues you know and those you don't!.

This week: Marije Behet






1. Name & Nationality
Marije Behet, Dutch

2. When you were a kid what did you want to be when you grew up?
When I was still a child in primary school, I wanted to become a medical doctor to help other people and discover a cure for AIDS.

3. What was your previous academic training, where did you study?
Given my keen interest in biological mechanisms involved in human health and disease, I have taken up my University studies in Biomedical Sciences at the Radboud University. During my Masters I focused on a major in Human Pathobiology and an additional track in Infectious Diseases. My first Master's internship at the Department of
Medical Microbiology (Medical Parasitology) greatly motivated me to continue my career in the field of malaria research. After having finished my studies, I was therefore excited I could continue working here, first as a Junior researcher and now as a PhD student.

4. What is your current function and what would you like to achieve?
Our incomplete understanding of protective immunity to malaria is a major stumble block for the development of an effective vaccine. Our research group has recently established a highly efficient immunization regimen against malaria (ChemoProphylaxis and Sporozoites, CPS-immunization) that induces long-lasting protection against malaria. This regimen is therefore an extremely valuable model to unravel mechanisms of anti-malarial protective immunity.

The aim of my PhD project is to delineate humoral and cellular immune mechanisms involved in CPS-induced protection. I hope that I will thereby contribute to a better understanding of which immune responses are involved in protection against malaria, and the identification of immune signatures of protection, currently absent, but badly needed.

5. The RIMLS motto is 'to understand molecular mechanisms of disease'. What does this mean for you?
The RIMLS motto is for me the main reason why I studied Biomedical Sciences; I am really interested in which mechanisms are involved in disease and/or health and how we can use this knowledge for developing therapeutic strategies. With respect to the development of an effective anti-malarial vaccine, I think it is essential to understand which immune responses play an important role in protection and which antigens are targeted by our immune cells.

6. What is the biggest motivation in your work?
The biggest motivation in my work is the patient. If we can develop an effective anti-malarial vaccine, we could prevent the suffering and death of many people.

7. What is your dream for the future?
My dream for the future is to make an important scientific contribution to our current understanding of protective immune responses against malaria, and that this knowledge will ultimately lead to the development of an effective anti-malarial vaccine.

8. Fun-facts. State an interesting/obscure fact about yourself together with two that are false? Correct answer will be revealed to readers in the subsequent edition.
A: I never hiked a long-distance trail.
B: I once spent the night at the lab for an experiment.
C: I can speak Spanish fluently.

Correct answer will be revealed to readers in the subsequent edition.


Correct answer of Janneke Hoogstad-Van Evert: B

State an interesting/obscure fact about yourself together with two that are false
6 years ago, I made a promise, that I am fulfilling this year:
A: that I would cure cancer.
B: that I would run the 'Zevenheuvelenloop'.
C: that I would do audition for Idols.



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