Bloemendal Medal 2013

Bertozzi, Carolyn

The Hans Bloemendal Medal for 2013 is awarded to Professor Carolyn Bertozzi, in recognition of her groundbreaking studies spanning the disciplines of chemistry and biology.

Carolyn Bertozzi is an internationally well-respected expert in glycans, and one of the pioneering scientists in the area of chemical biology. Her lab focuses on profiling changes in cell surface glycosylation associated with disease, and exploiting this information for development of diagnostic and therapeutic approaches. In a landmark paper in PNAS (2007) she developed copper-free click chemistry for dynamic imaging and then went on to further develop the technique forin vivoimaging of glycosylation in zebrafish (Science, 2008) and in mice (PNAS, 2010). This innovative approach uses bio-orthogonal laboratory-developed reagents that do not react with the normal molecules in the body, and thus do not interfere with the sugars' ability to carry out their normal signaling functions. Her work suggests that this technique could potentially be used to attach tracers to diseased cells. In addition to the diagnosis and treatment of disease, the techniques developed by Bertozzi also are being used in her laboratory to construct biocompatible materials, such as artificial bone and cartilage, with applications in medicine and in materials science. These findings hold great promise for the future of medicine and personalized healthcare.

Carolyn Bertozzi's enthusiasm for her research is matched by her talent for communicating science. She is an elected member of the National Academy of Sciences, the American Academy of Arts and Sciences and the Institute of Medicine. Including the Lemelson-MIT Prize, dubbed the 'Oscar for inventors', she has nearly 50 accolades to her name.

In summary, Carolyn Bertozzi is a world leader in glycobiology and chemical biology research. She has published more than 450 papers, which have been cited nearly than 20,000 times (current H-index 70). Her enthusiasm for science and intelligent approach to research is remarkable. We hope that Prof. Bertozzi feels honored by adding the Hans Bloemendal Medal from the Nijmegen Centre for Molecular Life Sciences (NCMLS) to her impressive list of achievements and awards.

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