CSC fellowships for NCMLS researchers

CSC

A number of NCMLS researchers have been successful in obtaining CSC scholarships for Chinese PhD students. The China Scholarship Council (CSC) is a non-profit institution affiliated with the Ministry of Education. The objective of the CSC is to provide financial assistance to the Chinese citizens wishing to study abroad and to the foreign citizens wishing to study in China.

 

 

 

 

 

Leonie Kamminga, Epigenetic regulation of tissue maintenance
Diao, Mingkun The identity of different tissues is specified during early embryonic development and subsequently needs to be maintained. These processes require precise control of specific transcriptional programs. Polycomb group proteins regulate transcription by establishing repressive chromatin modifications. The key objective of this study is to assess how Polycomb group proteins are involved in carcinogenesis and maintenance of adult tissues.

PhD student: Mingkun Diao

Colin Logie, Microbe-mediated epigenetic programming of human innate immunity responses
ManThe innate and acquired arms of the immune system cooperate closely to protect us from pathogens whilst allowing commensal colonization. The project will investigate the mechanisms by which the innate immune system, and in particular monocytic cells and their derivatives, respond to microbes and establish epigenomic markings of these encounters that persist for weeks if not months.

PhD student: Cheng Wang

Roland Kuiper, Improving prediction of relapse for childhood acute lymphoblastic leukemia through comprehensive subclonal analysis
Jiangyan Yu _sqRecent studies have shown a complex, dynamic architecture of clonal diversity in acute lymphoblastic leukemia and other leukemia subtypes, both at first diagnosis and at relapse. This multiclonal diversity follows a Darwinian model of evolution, and likely contributes to the selective outgrowth of therapy-resistant leukemic cells during or after chemotherapy treatment, resulting in relapse. The aim of this project is to investigate the multiclonal architecture of ALL in relation to therapy resistance and the origin of relapse and determine the clinical relevance of subclonal genetic abnormalities for treatment choices.

PhD student: Jiangyan Yu


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