Flier , Michiel Van Der
Dr. Michiel van der Flier 

Assistant Professor

Infectious diseases and global health


Michiel van der Flier is consultant in pediatric infectious diseases and immunology. He did his medical school at Utrecht University and as a student was a Guest Investigator at Rockefeller University, New York, USA, for one year. He trained in General Pediatrics at Utrecht University Medical Center and obtained his PhD degree on VEGF in sepsis and Meningitis at the same university. Subsequently he followed his subspecialty training at the ErasmusMC in Rotterdam and Great Ormond Street Hospital in London, UK. He combines clinical care for children with infectious diseases and immunodeficiencies with teaching and research. Brief Research Summary: Bacteria like the pneumococcus colonize all children but cause life-threatening infections in only a few. We examine the molecular determinants that distinguish those children that are at risk of severe bacterial infection (PeD-BIG network, FP-7 EUCLIDS-project). We study the molecular host response to bacteria in vitro in blood samples of children with a known high risk for severe bacterial infection: immunodeficiency (such as ataxia telangiectasia) or very young age (immunodeficiency of immaturity). We further perform experiments to clarify the exact effect of such factors for instance complement factor H. Preventive and therapeutic measures in high risk children are studied clinically.

National & International Personal Prizes & Awards

2006: ESPID Fellowship

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