Ditte Lundvig

Lundvig , Ditte
Dr. Ditte Lundvig 


Reconstructive and regenerative medicine


Our department houses the largest cleft-lip and palate (CLP) centre in the Netherlands. Here, patients with orofacial clefts are treated for years to correct the defect. A wide range of specialists are involved in this, and follow the patient from their baby years into young adulthood. One of the major complications experienced by the patients is the formation of excessive scar tissue after surgical cleft closure, leading to both esthetical and functional complications, like impaired development of jaw and dentition. Excessive scarring is the result of prolonged inflammation and oxidative stress as well as increased mechanical tissue loading in the growing child. Thus, the prevention of excessive scar formation would contribute positively to the lives of these patients. Unfortunately, still no effective anti-fibrotic therapies exist. We use different cell and animal models to study wound healing and scar formation, and we study the potential effect of cytoprotective and antioxidant molecules on these processes and aim to develop putative anti-fibrotic therapies.

Dr. Ditte Lundvig works as a postdoc in the Department of Orthodontics and Craniofacial Biology at Dentistry in the research groups of Dr. Frank Wagener and Dr. Hans Von den Hoff, where she is focusing on myofibroblast biology and anti-fibrotic strategies. She was recently awarded a TASENE research grant and several travel grants to continue her research.

National & International Personal Prizes & Awards

  • PhD Fellowship (2006-2007), Faculty of Health Sciences, University of Aarhus, Denmark
  • Travel Grant (congress visit 2012), Lundbeckfonden, Denmark
  • TASENE research grant "Novel therapies to reduce scarring and quality of life assessment in orofacial clefting" (2012-2014), Costech/WOTRO/SIDA
  • ERASMUS Staff-Training grant for EMBO Laboratory Management course participation (2012)

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