Vermeulen , Michiel2
Prof. Michiel Vermeulen 

Full Professor

Cancer development and immune defense


Our lab is using state-of-the-art quantitative mass-spectrometry based proteomics technology to identify and characterize proteins that interact with epigenetic DNA and histone modifications (so-called chromatin 'readers'). We characterize the complexes that these readers form and study their biology in (differentiated) stem cells and their potential deregulation in cancer. We are also globally quantifying dynamic (phospho)proteomes and other post-translational modifications in response to certain cellular stimuli/perturbations and during development. In addition to these mass spectrometry-based technologies, we are also integrating conventional protein biochemistry, CRISPR/Cas9, genomic sequencing (ChIP-seq, RNA-seq DNAseI-seq) and imaging approaches in our projects.

National & International Personal Prizes & Awards

  • 2008: Max Planck Institute for Biochemistry Junior Research Award
  • 2009: NWO VIDI 
  • 2012: ERC Starting Grant

Secondary functions


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